The short version of the story is that the DuRussels (with or without a capital 'R'?) were originally French Protestants (Huguenots) who fled to Switzerland to escape religious persecution by the Catholics. We also know that in the late 1800s, two young brothers from Payerne, Switzerland, came to the United States and settled in different areas of lower Michigan. Ironically, one of those brothers married a Catholic, thus resulting in numerous Catholic descendants who themselves were quite unaware (until recently) of the family's tormented past.
DuRussels can also be found in other countries such as France (no surprise there) and in Canada, where there are pockets of DuRussels primarily in Manitoba, Saskatchewan, and British Columbia. Similar to the story of the Michigan DuRussels, the Canadian DuRussels believe that their family's roots may be traceable to two brothers who fled from France, although they continue to do research on this topic.
Last, but not least, below is a photo of a plate with the Durussel family crest painted on it. This plate is proudly owned by a branch of the Durussel family residing in or near the city of Payerne, in the Canton of Vaud, Switzerland. A member of that family confirmed that 1569 is the year when the first Durussels left France to begin their new lives in Switzerland.